Preventer Plus (Milbemycin oxime & Lufenuron)
- Preventer Plus Flavor Tabs are given just once a month to prevent heartworm disease and flea populations in dogs and puppies.
- Controls flea populations and adult hookworms .
- Removes and controls adult roundworm and whipworm infection in dogs and puppies.
Product Detail: Preventer Plus (Milbemycin oxime & Lufenuron)
Preventer Plus Flavor Tabs
Preventer Plus Flavor Tabs (milbemycin oxime + lufenuron) are available in four tablet sizes in color-coded packages for oral administration to dogs and puppies according to their weight. Preventer Plus contains the same active ingredients as Sentinel® Flavor Tabs® (trademark Virbac Corporation). Each tablet is formulated to provide a minimum of 0.23 mg/lb (0.5 mg/kg) body weight of milbemycin oxime and 4.55 mg/pound (10 mg/kg) body weight of lufenuron. Milbemycin oxime consists of the oxime derivatives of 5-didehydromilbemycins in the ratio of approximately 80% A4 and 20% A3 Milbemycin oxime is classified as a macrocyclic antihelminthic.
Lufenuron is a benozylphenylurea derivative and classified as an insect develpoment inhibitor.
Preventer Plus Flavor Tabs are indicated for use in dogs and puppies, four weeks of age and older, and two pounds body weight or greater. Preventer Plus Flavor Tabs are indicated for the prevention of heartworm disease caused by Dirofilaria immitis, for the prevention and control of flea populations, the control of adult Ancylostoma caninum (hookworm), and the removal and control of adult Toxocara canis and Toxascaris leonina (roundworms) and Trichuris vulpis (whipworm) infections.
Lufenuron controls flea populations by preveting the development of flea eggs and does not kill adult fleas. Concurrent use of adulticide product may be necessary for adequate control of adult fleas.
Preventer Plus Flavor Tabs are given orally, once a month, at the recommended minimum dosage rate of 0.23 mg/lb (0.5mg/kg) milbemycin oxime and 4.55 mg/lb (10 mg/kg) lufenuron.
Dogs over 100 lbs are provided the appropriate combination of tablets.
To ensure adequate absorption, always administer Preventer Plus Flavor Tabs to dogs immediately after or in conjunction with a normal meal.
Recommended Dosage Schedule for Dogs
Dog Weight Milbemycin Oxime Per Tablet Lufenuron Per Tablet
2-10 lbs. 2.3 mg 46.0 mg
11-25 lbs. 5.75 mg 115 mg
26-50 lbs. 11.5 mg 230mg
51-100 lbs. 23.0 mg 460 mg
Preventer Plus Flavor Tabs are palatable and most dogs will consume the tablet when offered by the owner. As an alternative to direct dosing, the tablets can be hidden in food. Be certain the dog consumes the entire tablet. Administer Preventer Plus Flavor Tabs to dogs immediately after or in conjunction with a normal meal. Food is essential for adequate absorption of lufenuron. Watch the dog closely following administration to be sure the entire dose have been consumed
Preventer Plus Flavor Tabs must be administered monthly, preferably on the same date each month. Treatment may begin at any time of year. In geographic areas where mosquitoes and fleas are seasonal, the treatment schedule should begin one month prior to the expected onset and should continue until the end of mosquito and flea season. In areas with year-round infestations, treatment should continue through the entire year without interruption.
If a dose is missed and a 30-day interval between dosing is exceeded, administer Preventer Plus immediately and resume the monthly dosing schedule. If Preventer Plus Flavor Tabs replace daily diethylcarbamazine (DEC) for heartworm prevention, the first dose must be given within 30 days after the last dose of DEC.
Do not use in puppies less than four weeks of age and less than two pounds of body weight. Prior to initiation of the Preventer Plus Flavor Tabs treatment program, dogs should be tested for existing heartworm infections. Infected dogs should be treated to remove adult heartworms and microfilariae prior to initiating treatment with Preventer Plus Flavor Tabs. Mild transient hypersensitivity reactions manifested as labored respiration, vomiting, salivation and lethargy, have been noted in some treated dogs carrying a high number of circulating microfilariae. These reactions are presumably caused by release of protein from dead or dying microfilariae.
Preventer Plus Flavor Tabs immediately break the flea life cycle by inhibiting egg development. However, pre-existing flea populations may continue to develop and emerge after treatment has begun. Based on results of clinical studies, this emergence generally occurs during the first 30-60 days. Therefore, noticeable control may not be observed until several weeks after dosing when a pre-existing infestation is present.
If a Preventer Plus- treated dog comes in contact with a flea-infested environment, adult fleas may infest the treated animal. These adult fleas are unable to produce a viable offspring. The temporary use of an adulticide product may be necessary to kill these adult fleas.
Store in a dry place at controlled room temperature between 59° and 77°F (15-25°C).