Heartgard Plus Chewables
  • Heartgard Plus Chewables

Heartgard Plus Chewables

  • Highly effective dewormer that eliminates the tissue stages of heartworm larvae and removes adult roundworms and hookworms from dogs
  • Made with real beef and is a chewy treat for dogs
  • Easy to administer



From $34.95





Style Number: MSD24-CONFIG

Product Detail: Heartgard Plus Chewables

Heartgard Plus

Heartgard Plus is indicated for use in dogs to prevent canine heartworm disease by eliminating the tissue stage of heartworm larvae for a month (30 days) after infection, and for the treatment and control of roundworms and hookworms.


What are the active ingredients in Heartgard Plus?

Active ingredients: 


How Heartgard Plus works

Heartgard Plus prevents canine heartworm disease by eliminating the tissue stage of heartworm larvae (Dirofilaria immitis) for a month (30 days) after infection and for the treatment and control of ascarids (Toxocara canis, Toxascaris leonina) and hookworms (Ancylostoma caninum, Uncinaria stenocephala, Ancylostoma braziliense).


How can you properly administer Heartgard Plus?

Heartgard Plus (ivermectin/pyrantel) should be administered orally at monthly intervals at the recommended minimum dose level of 6 mcg of ivermectin per kilogram (2.72 mcg/lb) and 5 mg of pyrantel (as pamoate salt) per kg (2.27 mg/lb) of body weight. The recommended dosing schedule for the prevention of canine heartworm disease and for the treatment and control of ascarids and hookworms is as follows:

Dog Weight    Chewables per month    Ivermectin    Pyrantel    Color coding

Up to 25 lbs                        1                         68 mcg         57 mcg           Blue

26 to 50 lbs                        1                         136 mcg       114 mcg          Green

51 to 100 lbs                      1                         272 mcg       228 mcg          Brown

Heartgard Plus is recommended for dogs 6 weeks of age and older. For dogs over 100 lb use the appropriate combination of these chewables.


What are the precautions in using Heartgard Plus?

All dogs should be tested for existing heartworm infection before starting treatment with Heartgard Plus which is not effective against adult D. immitis. Infected dogs must be treated to remove adult heartworms and microfilariae before initiating a program with Heartgard Plus. While some microfilariae may be killed by the ivermectin in Heartgard Plus at the recommended dose level, Heartgard Plus is not effective for microfilariae clearance. A mild hypersensitivity-type reaction, presumably due to dead or dying microfilariae and particularly involving a transient diarrhea, has been observed in clinical trials with ivermectin alone after treatment of some dogs that have circulating microfilariae.


Ratings & Reviews

Based on 321 Review(s)

Average Rating


Ratings Overview











Most Recent Reviews

Same product as the Vet uses, just less $
Written by ypease
Apr 05, 2021

I like the idea I can order the same Heartworm meds from here at a lower price. The product it's self is effective at controling Heartworms, per my vet.

Great Product, Great Price
Written by ypease
Feb 18, 2021

The vet recommended this product for our new rescue. She is from Texas and there was no record re Heartworm testing. so the vet tested her and started her on HeartGard. She loves her HeartGard "treats". I have been buying it from Pet Shed since then. Pet Shed is the greatest! This product is the same as what's sold at the vet. No prescription, great service and shipping. I have been using Pet Shed for yrs now and have never been disappointed.

Long time user
Written by Steve d
Jun 26, 2020

I have been using this product from this supplier for ten years. Always good service and my three dogs have never had heartworm or internal parasites

Written by backwoodsbill
Apr 28, 2019

I have been using generic heartgard for three seasons and it has served my three Akita kids very well they have been heart worm free thank you Pet Shed

Absolute Savings
Written by Atlas
Apr 19, 2017

We may be new to Pet Shed but the first time we ordered this product back in 2016 gave us a new favorite Pet Store. Aside from their customer service who are very accommodating and lovely. Pet Shed made us realized that we can keep our pets from harm without spending a whole lot of money. Pet Shed is not just doing business but they're helping customer and our pets at the same time. We love you all!

Great product
Written by Blake
Jun 17, 2016

I trust this product 100%. My wife and I started taking care of a stray dog that was heart worm positive and the vet told us we could do the risky treatment that could possibly kill our new dog or we could do a long term treatment (HeartGard). we have been giving HeartGard to our dog for about 11 months now and there has been a huge improvement. Our dog no longer is wheasing or out of breath and she has tones of energy now and wants to play ALL THE TIME!

No Heartworm here!
Written by Lela Harnice
Jun 07, 2016

This Heargard medicine is so easy to administer and gives me peace of mind knowing my dog is protected. Super price and shipping!

Dogs love it!
Written by wdhutch
Jun 06, 2016

I've been using a much more expensive medication from my vet, and my dogs had to be bribed to take it. It was a whole ordeal, and my littlest one always had an upset stomach for a day or two following. This, however, seems like a treat to them! No upset tummies and much easier for them to take! And did I mention it is less expensive?

Excellent - HeartGard for cheaper!
Written by tm13
Jun 01, 2016

So grateful for PetShed! Heartgard is much cheaper than other pet websites and I don't need to pay for a heartworm test every time I get more. I have five dogs, and they all stay on heartworm preventative monthly, so saving money on a test AND the product is definitely helpful to me. The packaging is the same as the US, with of course the weight difference (pounds vs kilograms). Highly recommend this company.

good value product
Written by Amanda
May 18, 2016

I have ordered Heartgard for my dog from Petshed for several years. It is the best price I have found. I have had no issues with the product and costumer service was very helpful when I had a question. Will continue to order from Petshed.