Generic Frontline Plus (Fipronil & S-Methoprene)

Contains exactly the same active ingredients as Frontline Plus. You get the same fast, effective and convenient treatment and control of fleas, ticks and chewing lice at half the price of the brand name Frontline Plus!

  • Treats and prevents flea infestation and biting lice.
  • Has a rapid onset of action and kills re-infections with newly acquired adult fleas for at least one month.
  • Prevents the development of flea eggs, larvae and pupae produced by adult fleas acquired for six weeks after treatment.
  • May be used for the treatment of flea allergy dermatitis.
  • Easy to administer spot-on application
  • Each tube contains Fipronil & S-Methoprene

From $25.95






Product Detail: Generic Frontline Plus (Fipronil & S-Methoprene)

Information about Generic Frontline Plus

Generic Frontline Plus provides fast, effective and convenient treatment and control of fleas, ticks, and chewing lice. Treatment and prevention of flea infestation (Ctenocephalides spp) and control of ticks (Rhipicephalussanguineus), paralysis tick (Ixodes holocyclus) and biting lice (Trichodectes canis). Generic Frontline Plus has a rapid onset of action and kills re-infections with newly acquired adult fleas for at least one month. Generic Frontline Plus also prevents the development of flea eggs, larvae and pupae produced by adult fleas in 3 months after treatment. It controls brown ticks up to one month and paralysis ticks for up to two weeks after application. Checking your pets regularly is necessary to minimize the risk of tick paralysis. Checking should continue throughout the paralysis tick season. Generic Frontline Plus may be used for the treatment and control of flea allergy dermatitis. It is used for flea control as it breaks the life cycle of all stages of fleas.

Treatment Frequency

Recommended Dosage

Dosage Active Ingredients For cats
Generic Frontline Plus for Cats (Purple Box)
0.5 mL/pipette Fipronil 9.8% w/v; (S)-Methoprene 11.8% w/v 8 weeks or older
Dosage Concentration For dogs weighing
Generic Frontline Plus for Dogs (Blue Box)
0.67 mL/pipette Fipronil 9.8% w/v; (S)-Methoprene 8.8% w/v Up to 10kg
Generic Frontline Plus for Dogs (Red Box)
1.34 mL Fipronil 9.8% w/v; (S)-Methoprene 8.8% w/v 10-20 kg
Generic Frontline Plus for Dogs (Maroon Box)
2.68 mL Fipronil 9.8% w/v; (S)-Methoprene 8.8% w/v 20-40 kg
Generic Frontline Plus for Dogs (Green Box)
4.02 mL Fipronil 9.8% w/v; (S)-Methoprene 8.8% w/v 40-60 kg

Application: Break the snap-off top from the pipette along the scored line. Part the hair at the back, at the base of the neck,a nd between the shoulder blades until the skin is visible. Place the tip of the pipette onto the skin. Care should be taken to avoid excessive wetting of hair during treatment. Do not allow treated dogs/cats to lick each other or rub against other animals until the application site is dry.

Caution: Hazardous to humans. This product may cause irritation of mucous membranes, skin and eyes. Avoid contact of the product with the mouth, skin or eyes. Dogs/Cats or those who have known hypersensitivity to insecticides or alcohol should avoid contact with the drug. Avoid contact of contents with the fingers. If this occurs, wash hands with soap and water. In case of accidental exposure with eyes, rinse with clean water carefully. Do not handle treated dogs/cats and don't allow children to play with treated dogs/cats until the application site is dry. It is therefore recommended that cats/dogs should not be treated during the day but in the early evening and for treated cats not to sleep with owners, especially children. Do not smoke, drink, or eat during application. Do not apply Generic Frontline Plus for more than 30 days.

Safety in Dogs/ Cats. For external use only. Generic Frontline Plus is safe for use in dogs and puppies, cats and kittens over 8 weeks of age and in breeding, pregnant or lactating bitches/queens. Do not use Generic Frontline Plus if you or your pet has a known hypersensitivity to insecticides or alcohol.

If swallowed call a poison control center or doctor immediately for treatment advice. For hazards to domestic animals the 24 hour assistance line within the U.S.A. is 1-800-660-1842.

Storage: Store below 30 C in dark place. Protect from heat.

Physical or Chemical hazards: Flammable. Keep away from heat and open flame.

Container disposal: Fipronil and (S)-methoprene may adversely affect aquatic organisms. Do not discard the product or empty pipettes in ponds, rivers and streams. Securely wrap bottles in several layers and discard in trash.

Ratings & Reviews

Based on 446 Review(s)

Average Rating


Ratings Overview











Most Recent Reviews

Best Deal In Town
Written by sara
Jan 27, 2018

I always buy my pet meds from Pet Shed! My vet says they price match, but when they see the amazing deals I get from Pet Shed they can't match it. I order everything here, one low shipping fee and no back and forth trips to the vet. So simple. I wish everyone knew how easy this is.

Effective product but bad smell
Written by Alison B
Oct 31, 2017

This product works very well and is a much cheaper alternative to Frontline. Just a warning to anyone that hasn't tried yet - it does have a strong fish smell that lasts a day, maybe 2 at most. But it does go away. I would recommend this to anyone wanting a cheaper alternative. The current stock expires in May 2018, so unfortunately could only buy the 6 month supply when I was hoping to buy a 12 month supply.

Money saver!
Written by Linda Author
Jun 07, 2017

Everyone who came here to say this product can save us lots of money! It's just amazing! This works well though there are downsides like the smell but overall this is amazing! What's important is it works the way it is supposed to be.

The best
Written by jill
Feb 28, 2017

I am so pleased with how this product works. It has saved me tons of money and kept the fleas away

Simply amazing!
Written by Queen P
Jan 31, 2017

This product is as effective as the original brand and it really works well it's just that the smell of this is a lil bit strong. But anyway I have saved a lot of savings and made my baby safe. It's like I hit two birds in one stone with this Product! Thanks Pet Shed! Cheers!

PARA shield Plus
Written by Carol
Oct 31, 2016

Kills fleas on my cats instantly. Great product to use.

Written by Jeremy
Oct 28, 2016


generic frontline plus
Written by Pia
Oct 20, 2016

Great alternative to vet's expensive prices!! A tight budget is really not a problem to Pet Shed!

Flea solution for my dog
Written by Sam
Oct 14, 2016

I bought this 2months ago and so far I'm very happy with the results. Fleas were really lessen in just one application! I can't wait for all of those fleas to be gone.

Written by ALLISON
Oct 13, 2016

Buy generic frontline plus and you'll love it. You'll actually love the savings!