Frontline Plus Frontline Plus View 1

Frontline Plus

User Rating
4.8 / 5

Frontline Plus features

  • Kills fleas for at least one month
  • Controls and treats Flea Allergy Dermatitis
  • Kills all known ticks for at least one month
  • Water-resistant
  • Easy to administer spot-on application
  • Each tube contains Fipronil & S-Methoprene
Size Price Qty Add
3 Pack
$33.95
6 Pack
$57.95
12 Pack
$108.95
3 Pack
$33.95
6 Pack
$57.95
12 Pack
$108.95
3 Pack
$34.95
6 Pack
$60.95
12 Pack
$113.95
3 Pack
$37.95
6 Pack
$63.95
12 Pack
$119.95
3 Pack
$38.95
6 Pack
$65.95
12 Pack
$123.95

Information about Frontline Plus

Frontline Plus provides protection against fleas and ticks, and contains a special ingredient to kill flea eggs and larvae. By stopping the development of new fleas, Frontline Plus provides the most complete flea and tick protection available. Frontline Plus kills 100% of fleas and ticks within 48 hours, including many ticks that transmit dangerous diseases that can affect other pets and humans.

Frontline Plus Flea Control has been formulated for use on puppies and kittens from eight weeks of age and is safe for use on pregnant and lactating animals. It is a water-resistant flea medication, so it continues to kill fleas even after shampooing, swimming, rain or exposure to sunlight.

Learn More About Frontline Plus

Product Information Schedule

N.B. Pet Shed sells the Australian versions of the products listed below.
Metric conversion: 1 kg = 2.2 lbs

  Dosage Active Ingredients For cats
Frontline Plus for Cats (Green Box)      
Australian Version, NRA Approval No. 54524 0.5 mL 100 g/L Fipronil & 120 g/L (S)-Methoprene 8 weeks or older
USA Version, EPA Reg. No. 65331-4 0.017 fl oz (0.5 ml) 9.8% Fipronil & 11.8% (S)-Methoprene (by weight) 8 weeks or older
  Dosage Concentration For dogs weighing
Frontline Plus for Dogs (Orange Box)      
Australian Version, NRA Approval No. 54523 0.67 mL 100 g/L Fipronil & 90 g/L (S)-Methoprene Up to 10kg
USA Version, EPA Reg. No. 65331-5 0.023 fl oz (0.67 mL) 9.8% Fipronil & 8.8% (S)-Methoprene (by weight) Up to 22 lbs
Frontline Plus for Dogs (Blue Box)      
Australian Version, NRA Approval No. 54523 1.34 mL 100 g/L Fipronil & 90 g/L (S)-Methoprene 10-20 kg
USA Version, EPA Reg. No. 65331-5 0.045 fl oz (1.34 mL) 9.8% Fipronil & 8.8% (S)-Methoprene (by weight) 23-44 lbs
Frontline Plus for Dogs (Purple Box)      
Australian Version, NRA Approval No. 54523 2.68 mL 100 g/L Fipronil & 90 g/L (S)-Methoprene 20-40 kg
USA Version, EPA Reg. No. 65331-5 0.091 fl oz (2.68 mL) 9.8% Fipronil & 8.8% (S)-Methoprene (by weight) 45-88 lbs
Frontline Plus for Dogs (Red Box)      
Australian Version, NRA Approval No. 54523 4.02 mL 100 g/L Fipronil & 90 g/L (S)-Methoprene 40-60 kg
USA Version, EPA Reg. No. 65331-5 0.136 fl oz (4.02 mL) 9.8% Fipronil & 8.8% (S)-Methoprene (by weight) 89-132 lbs

Frontline Plus has been approved for sale in Australia by the APVMA. The US equivalent of this product has been approved for sale by the EPA.

Both the Australian and US products contain the same active ingredients, Fipronil & (S)-Methoprene.

However, the products sold by Pet Shed are sold in Australian packaging which has not been approved for sale in the US. As a consequence, the Australian packaging does not have EPA approval and the sale and purchase of products in the Australian packaging may be illegal in the US.

If swallowed call a poison control center or doctor immediately for treatment advice. For hazards to domestic animals the 24 hour assistance line within the U.S.A. is 1-800-660-1842.

The Product Information Schedule above indicates some of the material differences between the Australian and U.S.A. versions.

Style Number: MSD14-CONFIG

Customer Reviews

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5 out of 5
Overall Customer Average (337 reviews) Write Review

5 out of

Used Frontline for my dog for 10 years in Texas!

Date: Jul 22, 2015

There have been no fleas or ticks on my dog in Houston, Texas in the past 10 years because I have used Frontline! I found it much less expensive on the Pet Shed website than in the United States and it is so convenient to order. It is delivered in about a week from PetShed to the USA.

Written by: sbparker

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5 out of

Frontline Plus

Date: Jun 30, 2015

I've been buying Frontline Plus for several years from PetShed.com and am pleased with the product, expiration dates have always been great, and it ships pretty fast as well.

Written by: Jeasta

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5 out of

Frontline Plus/Pet Shed Service

Date: Jun 06, 2015

Pet Shed is where I purchase Frontline Plus (6 pack) for my 3 small dogs. I need to purchase Frontline to keep the fleas off them. Frontline works for them. From what I have been able to research Pet Shed is the economical way to go to purchase this product. All the other stores and vet offices around my area offer Frontline but their prices are crazy expensive. Thank you Pet Shed for providing this product at a decent cost.

Written by: Yolanda

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5 out of

Great product

Date: May 29, 2015

Although Frontline Plus is only only product I've ever used on my Golden Retriever (she's now 5 years old), I've used it every month and never had any problems with fleas or ticks. It's great when a product works as advertised.

Written by: Kristof

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5 out of

flea and tick

Date: May 21, 2015

Love front line. Been using it on my pets for years and will continue to do so.

Written by: Echoe

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