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Frontline Plus

User Rating
4.8 / 5

Information about Frontline Plus

Frontline Plus provides protection against fleas and ticks, and contains a special ingredient to kill flea eggs and larvae. By stopping the development of new fleas, Frontline Plus provides the most complete flea and tick protection available. Frontline Plus kills 100% of fleas and ticks within 48 hours, including many ticks that transmit dangerous diseases that can affect other pets and humans.

Frontline Plus Flea Control has been formulated for use on puppies and kittens from eight weeks of age and is safe for use on pregnant and lactating animals. It is a water-resistant flea medication, so it continues to kill fleas even after shampooing, swimming, rain or exposure to sunlight.

Frontline Plus features

  • Kills fleas for at least one month
  • Controls and treats Flea Allergy Dermatitis
  • Kills all known ticks for at least one month
  • Water-resistant
  • Easy to administer spot-on application
  • Each tube contains Fipronil & S-Methoprene
Size Price Qty Add
3 Pack
$33.95
6 Pack
$57.95
12 Pack
$108.95
3 Pack
$33.95
6 Pack
$57.95
12 Pack
$108.95
3 Pack
$34.95
6 Pack
$60.95
12 Pack
$113.95
3 Pack
$37.95
6 Pack
$63.95
12 Pack
$119.95
3 Pack
$38.95
6 Pack
$65.95
12 Pack
$123.95

Learn More About Frontline Plus

Product Information Schedule

N.B. Pet Shed sells the Australian versions of the products listed below.
Metric conversion: 1 kg = 2.2 lbs

Dosage Active Ingredients For cats
Frontline Plus for Cats (Green Box)
Australian Version, NRA Approval No. 54524 0.5 mL 100 g/L Fipronil & 120 g/L (S)-Methoprene 8 weeks or older
USA Version, EPA Reg. No. 65331-4 0.017 fl oz (0.5 ml) 9.8% Fipronil & 11.8% (S)-Methoprene (by weight) 8 weeks or older
Dosage Concentration For dogs weighing
Frontline Plus for Dogs (Orange Box)
Australian Version, NRA Approval No. 54523 0.67 mL 100 g/L Fipronil & 90 g/L (S)-Methoprene Up to 10kg
USA Version, EPA Reg. No. 65331-5 0.023 fl oz (0.67 mL) 9.8% Fipronil & 8.8% (S)-Methoprene (by weight) Up to 22 lbs
Frontline Plus for Dogs (Blue Box)
Australian Version, NRA Approval No. 54523 1.34 mL 100 g/L Fipronil & 90 g/L (S)-Methoprene 10-20 kg
USA Version, EPA Reg. No. 65331-5 0.045 fl oz (1.34 mL) 9.8% Fipronil & 8.8% (S)-Methoprene (by weight) 23-44 lbs
Frontline Plus for Dogs (Purple Box)
Australian Version, NRA Approval No. 54523 2.68 mL 100 g/L Fipronil & 90 g/L (S)-Methoprene 20-40 kg
USA Version, EPA Reg. No. 65331-5 0.091 fl oz (2.68 mL) 9.8% Fipronil & 8.8% (S)-Methoprene (by weight) 45-88 lbs
Frontline Plus for Dogs (Red Box)
Australian Version, NRA Approval No. 54523 4.02 mL 100 g/L Fipronil & 90 g/L (S)-Methoprene 40-60 kg
USA Version, EPA Reg. No. 65331-5 0.136 fl oz (4.02 mL) 9.8% Fipronil & 8.8% (S)-Methoprene (by weight) 89-132 lbs

Frontline Plus has been approved for sale in Australia by the APVMA. The US equivalent of this product has been approved for sale by the EPA.

Both the Australian and US products contain the same active ingredients, Fipronil & (S)-Methoprene.

However, the products sold by Pet Shed are sold in Australian packaging which has not been approved for sale in the US. As a consequence, the Australian packaging does not have EPA approval and the sale and purchase of products in the Australian packaging may be illegal in the US.

If swallowed call a poison control center or doctor immediately for treatment advice. For hazards to domestic animals the 24 hour assistance line within the U.S.A. is 1-800-660-1842.

The Product Information Schedule above indicates some of the material differences between the Australian and U.S.A. versions.

Style Number: MSD14-CONFIG

Customer Reviews

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5 out of 5
Overall Customer Average (263 reviews) Write Review

4 out of

I'M baaaack!

Date: Jan 15, 2013

This is the best ever to buy Frontline Plus for dogs!! My last order I even called PS help me. They were very helpful!! The BEST prices ever!! I will always order from PS as I have 2 dogs and I watch the prices! Again I do like Pet Shed a lot!!

Written by: Phyllis

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5 out of

Best Flea Defense

Date: Jan 08, 2012

I have a Lab sized dog. I have been buying Frontline plus from Pet Shed for several years now. The lower price makes it possible to treat my dog year round. Living in Arizona with an allergy prone dog, that's a real PLUS. It seems to be the exact same high quality product as is available in pet stores or vet's offices. The shipping hasn't been as fast as I expected the last couple of times I ordered but my order still arrives within 3 weeks. Both times after calling or sending an email, customer service has been very quick to address my concern or call with information.

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5 out of

Fleas be gone

Date: Jan 01, 2012

I use Frontline Plus on my dog because the product always takes care of the fleas and flea eggs by zapping them dead. My dog never scratches or bits herself because the fleas never bite her! I have used this product on my dog for several years and have never had any flea allergy problems, the service from Pet Shed is excellent and the items always arrive promptly.

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5 out of

Frontline Plus is GREAT

Date: Dec 22, 2011

I've been using Frontline Plus from Pet Shed for many years now, and I won't use anything else unless Pet Shed stops sending it to the USA. I like the fact that I don't have to worry about grooming the dogs, because I can apply it as soon as they are dry or they can be bathed as soon as the medication has dried on their skin. I don't have to worry about allergies, because in all my years of dog raising, I've NEVER had a dog be allergic to it. I don't have to worry about ticks and fleas because Frontline Plus keeps those little beasties OFF my animals! I have both dogs and cats, and use Frontline Plus for both.

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5 out of

Most worthwhile purchase

Date: Dec 20, 2011

This product is now something our household cannot do without. We had a feral cat take up residence with us, and we watched him suffer with awful flea torture for months before we were able to touch him. Once we were able to touch him, we were able to quickly/stealthily apply the Frontline for him. His immediate comfort was evident, and his life has been changed utterly. We don't have to worry about a house flea infestation now, either. Thank you, Frontline, for a wonderful product that is very easy to apply and doesn't require a large dose to work perfectly.

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