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Frontline Plus

User Rating
4.7 / 5

Frontline Plus features

  • Kills fleas for at least one month
  • Controls and treats Flea Allergy Dermatitis
  • Kills all known ticks for at least one month
  • Water-resistant
  • Easy to administer spot-on application
  • Each tube contains Fipronil & S-Methoprene

Select the generic alternative and save even more $$$

Generic Frontline
Generic Frontline
Generic Frontline
Generic Frontline
Generic Frontline
Size Price Qty Add
(Generic brand) 3 Pack
$14.95
(Original brand) 3 Pack
$33.95
(Generic brand) 6 Pack
$25.95
(Original brand) 6 Pack
$56.95
(Generic brand) 12 Pack
$49.95
(Original brand) 12 Pack
$113.95
(Generic brand) 3 Pack
$14.95
(Original brand) 3 Pack
$33.95
(Generic brand) 6 Pack
$25.95
(Original brand) 6 Pack
$56.95
(Generic brand) 12 Pack
$49.95
(Original brand) 12 Pack
$113.95
(Generic brand) 3 Pack
$15.95
(Original brand) 3 Pack
$35.95
(Generic brand) 6 Pack
$27.95
(Original brand) 6 Pack
$59.95
(Generic brand) 12 Pack
$54.95
(Original brand) 12 Pack
$118.95
(Generic brand) 3 Pack
$16.95
(Original brand) 3 Pack
$37.95
(Generic brand) 6 Pack
$28.95
(Original brand) 6 Pack
$62.95
(Generic brand) 12 Pack
$56.95
(Original brand) 12 Pack
$124.95
(Generic brand) 3 Pack
$17.95
(Original brand) 3 Pack
$39.95
(Generic brand) 6 Pack
$29.95
(Original brand) 6 Pack
$65.95
(Generic brand) 12 Pack
$58.95
(Original brand) 12 Pack
$130.95

Information about Frontline Plus

Frontline Plus provides protection against fleas and ticks, and contains a special ingredient to kill flea eggs and larvae. By stopping the development of new fleas, Frontline Plus provides the most complete flea and tick protection available. Frontline Plus kills 100% of fleas and ticks within 48 hours, including many ticks that transmit dangerous diseases that can affect other pets and humans.

Frontline Plus Flea Control has been formulated for use on puppies and kittens from eight weeks of age and is safe for use on pregnant and lactating animals. It is a water-resistant flea medication, so it continues to kill fleas even after shampooing, swimming, rain or exposure to sunlight.

Learn More About Frontline Plus

Product Information Schedule

N.B. Pet Shed sells the Australian versions of the products listed below.
Metric conversion: 1 kg = 2.2 lbs

  Dosage Active Ingredients For cats
Frontline Plus for Cats (Green Box)      
Australian Version, NRA Approval No. 54524 0.5 mL 100 g/L Fipronil & 120 g/L (S)-Methoprene 8 weeks or older
USA Version, EPA Reg. No. 65331-4 0.017 fl oz (0.5 ml) 9.8% Fipronil & 11.8% (S)-Methoprene (by weight) 8 weeks or older
  Dosage Concentration For dogs weighing
Frontline Plus for Dogs (Orange Box)      
Australian Version, NRA Approval No. 54523 0.67 mL 100 g/L Fipronil & 90 g/L (S)-Methoprene Up to 10kg
USA Version, EPA Reg. No. 65331-5 0.023 fl oz (0.67 mL) 9.8% Fipronil & 8.8% (S)-Methoprene (by weight) Up to 22 lbs
Frontline Plus for Dogs (Blue Box)      
Australian Version, NRA Approval No. 54523 1.34 mL 100 g/L Fipronil & 90 g/L (S)-Methoprene 10-20 kg
USA Version, EPA Reg. No. 65331-5 0.045 fl oz (1.34 mL) 9.8% Fipronil & 8.8% (S)-Methoprene (by weight) 23-44 lbs
Frontline Plus for Dogs (Purple Box)      
Australian Version, NRA Approval No. 54523 2.68 mL 100 g/L Fipronil & 90 g/L (S)-Methoprene 20-40 kg
USA Version, EPA Reg. No. 65331-5 0.091 fl oz (2.68 mL) 9.8% Fipronil & 8.8% (S)-Methoprene (by weight) 45-88 lbs
Frontline Plus for Dogs (Red Box)      
Australian Version, NRA Approval No. 54523 4.02 mL 100 g/L Fipronil & 90 g/L (S)-Methoprene 40-60 kg
USA Version, EPA Reg. No. 65331-5 0.136 fl oz (4.02 mL) 9.8% Fipronil & 8.8% (S)-Methoprene (by weight) 89-132 lbs

Frontline Plus has been approved for sale in Australia by the APVMA. The US equivalent of this product has been approved for sale by the EPA.

Both the Australian and US products contain the same active ingredients, Fipronil & (S)-Methoprene.

However, the products sold by Pet Shed are sold in Australian packaging which has not been approved for sale in the US. As a consequence, the Australian packaging does not have EPA approval and the sale and purchase of products in the Australian packaging may be illegal in the US.

If swallowed call a poison control center or doctor immediately for treatment advice. For hazards to domestic animals the 24 hour assistance line within the U.S.A. is 1-800-660-1842.

The Product Information Schedule above indicates some of the material differences between the Australian and U.S.A. versions.

Style Number: MSD14-CONFIG

Customer Reviews

Sort Order:

5 out of 5
Overall Customer Average (373 reviews) Write Review

2 out of

Generic Frontline Smells Bad

Date: Sep 02, 2016

I agree with the other reviews that the generic Frontline smells very bad so beware. The smell only lasts a few days so if you can put up with that it is OK, but it reminds me of a liquid fly trap I once bought - smell was horrible but it sure worked on flies. I am throwing this stuff away and ordering the real Frontline.

Written by: Wrangler50

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0 out of

Generic brand

Date: Aug 17, 2016

We have always used Frontline plus, however we tried the generic brand because it was less expensive. It was not a good choice. Our dogs stayed covered in fleas. Frontline has been the best choice for us.

Written by: M B

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0 out of

BEWARE: Generic is NOT the Same

Date: Aug 03, 2016

I used the generic Frontline on my medium dog and used the brand name on my small dog. The brand name had almost no odor, and dried within just a few minutes. The generic had an overwhelmingly bad odor (a mix of chemicals and fish), and 3 hours later was still not dry and still smelled bad. The generic stuff was so horrible that I threw the remaining treatments away. I'm just grateful my dog didn't have a bad reaction to the stuff (other than rolling in dirt 3 hours later in an attempt to get rid of it).

Written by: Holly C

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4 out of

Pet Shed Products

Date: Jul 08, 2016

I absolutely love Pet Shed Product; they are great as well as cheaper. You service is Wonderful. I only have one problem, I am having trouble ordering Fiprofort for Cats! Thank You for your wonderful Service. Mary Blessing

Written by: Mary J. Blessing

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3 out of

Generic Warning

Date: Jul 06, 2016

We are in FL and have always used Frontline+, but we decided to try out the generic version this time. Just put it on our dog today and I don't know how well it is going to work, but buyer beware the product smells like dead fish! When I contacted PetShed they said the smell is normal and that does not mean the product is bad. Just something to keep in mind before you get stuck with a 6-12 month supply.

Written by: Master Jedi

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