Frontline Plus

User Rating
4.7 / 5

Frontline Plus features

  • Kills fleas for at least one month
  • Controls and treats Flea Allergy Dermatitis
  • Kills all known ticks for at least one month
  • Water-resistant
  • Easy to administer spot-on application
  • Each tube contains Fipronil & S-Methoprene
Size Price Qty Add
3 Pack
$33.95
6 Pack
$56.95
12 Pack
$113.95
3 Pack
$33.95
6 Pack
$56.95
12 Pack
$113.95
3 Pack
$35.95
6 Pack
$59.95
12 Pack
$118.95
3 Pack
$37.95
6 Pack
$62.95
12 Pack
$124.95
3 Pack
$39.95
6 Pack
$65.95
12 Pack
$130.95

Information about Frontline Plus

Frontline Plus provides protection against fleas and ticks, and contains a special ingredient to kill flea eggs and larvae. By stopping the development of new fleas, Frontline Plus provides the most complete flea and tick protection available. Frontline Plus kills 100% of fleas and ticks within 48 hours, including many ticks that transmit dangerous diseases that can affect other pets and humans.

Frontline Plus Flea Control has been formulated for use on puppies and kittens from eight weeks of age and is safe for use on pregnant and lactating animals. It is a water-resistant flea medication, so it continues to kill fleas even after shampooing, swimming, rain or exposure to sunlight.

Learn More About Frontline Plus

Product Information Schedule

N.B. Pet Shed sells the Australian versions of the products listed below.
Metric conversion: 1 kg = 2.2 lbs

  Dosage Active Ingredients For cats
Frontline Plus for Cats (Green Box)      
Australian Version, NRA Approval No. 54524 0.5 mL 100 g/L Fipronil & 120 g/L (S)-Methoprene 8 weeks or older
USA Version, EPA Reg. No. 65331-4 0.017 fl oz (0.5 ml) 9.8% Fipronil & 11.8% (S)-Methoprene (by weight) 8 weeks or older
  Dosage Concentration For dogs weighing
Frontline Plus for Dogs (Orange Box)      
Australian Version, NRA Approval No. 54523 0.67 mL 100 g/L Fipronil & 90 g/L (S)-Methoprene Up to 10kg
USA Version, EPA Reg. No. 65331-5 0.023 fl oz (0.67 mL) 9.8% Fipronil & 8.8% (S)-Methoprene (by weight) Up to 22 lbs
Frontline Plus for Dogs (Blue Box)      
Australian Version, NRA Approval No. 54523 1.34 mL 100 g/L Fipronil & 90 g/L (S)-Methoprene 10-20 kg
USA Version, EPA Reg. No. 65331-5 0.045 fl oz (1.34 mL) 9.8% Fipronil & 8.8% (S)-Methoprene (by weight) 23-44 lbs
Frontline Plus for Dogs (Purple Box)      
Australian Version, NRA Approval No. 54523 2.68 mL 100 g/L Fipronil & 90 g/L (S)-Methoprene 20-40 kg
USA Version, EPA Reg. No. 65331-5 0.091 fl oz (2.68 mL) 9.8% Fipronil & 8.8% (S)-Methoprene (by weight) 45-88 lbs
Frontline Plus for Dogs (Red Box)      
Australian Version, NRA Approval No. 54523 4.02 mL 100 g/L Fipronil & 90 g/L (S)-Methoprene 40-60 kg
USA Version, EPA Reg. No. 65331-5 0.136 fl oz (4.02 mL) 9.8% Fipronil & 8.8% (S)-Methoprene (by weight) 89-132 lbs

Frontline Plus has been approved for sale in Australia by the APVMA. The US equivalent of this product has been approved for sale by the EPA.

Both the Australian and US products contain the same active ingredients, Fipronil & (S)-Methoprene.

However, the products sold by Pet Shed are sold in Australian packaging which has not been approved for sale in the US. As a consequence, the Australian packaging does not have EPA approval and the sale and purchase of products in the Australian packaging may be illegal in the US.

If swallowed call a poison control center or doctor immediately for treatment advice. For hazards to domestic animals the 24 hour assistance line within the U.S.A. is 1-800-660-1842.

The Product Information Schedule above indicates some of the material differences between the Australian and U.S.A. versions.

Style Number: MSD14-CONFIG

Customer Reviews

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5 out of 5
Overall Customer Average (362 reviews) Write Review

5 out of

Frontline Plus for cats

Date: Jan 26, 2016

I've been using this for several years (10+) now and have never found anything better. I trust this product and have not had any reason to doubt it's efficiency.

Written by: just me

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5 out of

frontline plus

Date: Nov 03, 2015

I love this product, but more important my dogs love it. don't have to hide in a treat, it is a treat. love the fantastic price and fast shipping

Written by: jan

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5 out of

15 Years of Protection

Date: Oct 25, 2015

Frontline and PetShed have provided safe, reliable and effective protection for my 15-year-old Jack Russell terrier.

Written by: Watash1999

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5 out of

Frontline Plus

Date: Oct 24, 2015

This product is wonderful! I give it monthly to my 3 dogs and they have absolutely no fleas or ticks. I would not even consider using another product on my beloved children. This product helps me protect them and that's something I take seriously.

Written by: Melanye Coursey

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4 out of

Happy Dogs

Date: Oct 02, 2015

We are very happy with our products from Pet Shed...no fleas, no ticks and we live in Flea country Florida....and have used Frontline Plus from Pet Shed for years. Will continue to use it on all my greyhounds, it's safe and I have no bad reactions from this product. The service is great too.

Written by: Diane

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