 Synotic Solution
 View other items in the same category as Synotic Solution Product UsesSynotic Otic Solution is indicated for the relief of itching and inflammation associated with acute and chronic ear infections in the dog. Product ContainsFluocinolone acetonide 0.01% and dimethyl sulfoxide 60% Dosage and AdministrationThe recommended dose of Synotic Otic Solution is 4 to 6 drops (0.2 mL) per ear administered twice daily into the ear canal for a maximum period of 14 days. The total dosage used should not exceed 17 mL. Clean the ear(s) prior to instilling the medication. Following instillation, gentle external massage of the ear canal may aid in promoting an even distribution of the medication. Avoid contact of the medication with the dog’s eyes. Contact of the bare hand with the medication should also be avoided. Warnings, Side Effects and Drug InteractionsA transient, but mild, stinging sensation may be experienced by some animals when the solution is applied to denuded areas. The effect will disappear as healing progresses. A temporary increase in temperature of the area may also be noted. Some animals may exhibit unfavorable local and/or systemic reaction to the medication, due to sensitization to one of the components of the solution. Corticosteroid therapy will generally cause a remission of signs of allergic origin. However, until the causative agent is identified and removed from the animal’s environment, the condition may recur when therapy is terminated. It is known that DMSO enhances the absorption of topically applied corticosteroids and the veterinarian should be aware of possible systemic reactions in this situation. Accordingly, this product is contraindicated wherever systemic corticosteroids would be dangerous. Adrenal suppression, weight loss and increased susceptibility to infections may be evidenced with the use of this drug, especially in overdosage. Therefore, care should be taken to assure that the recommended dosage is not exceeded. In the presence of local and/or systemic side effects, the drug should be withdrawn. When a local reaction occurs other therapeutic measures should be instituted. Therapy can usually be resumed at a lower dose once systemic signs abate, without further recurrence of the problem. Absorption of DMSO following topical application may result in an odorous breath described as oyster or garlic-like with an unpleasant taste. These effects are transient and not considered to be serious. Damage to eyes has been recorded in association with DMSO Preparations with DMSO should not be used in pregnant animals since studies in chick embryos and guinea pigs have indicated it is teratogenic and embryotoxic. Corticosteroids (such as fluocinolone acetonide) may induce the first stage of the birth process if used during the last trimester of pregnancy and may precipitate premature labor, which may be associated with complications. Additionally, corticosteroids administered to dogs, rabbits and rodents during pregnancy have resulted in birth defects in the young. DMSO is a potent solvent and may have a deleterious effect upon fabrics, plastics and other materials. Contact with the treated area should be avoided until drying of the treated ear canal has occurred. StorageClose vial tightly after use. Avoid freezing and excessive heat. ManufacturerFort Dodge Animal Health Federal law restricts this drug to use by or on the order of a licensed veterinarian.
|
