 Dicural
 View other items in the same category as Dicural Product UsesDicural tablets are indicated for the management of diseases in dogs associated with bacteria susceptible to difloxacin. Clinical efficacy was confirmed in skin and soft tissue infections (wounds and abscesses) and urinary tract infections (cystitis). Product ContainsDifloxacin hydrochloride Dosage and AdministrationThe dose range of difloxacin in dogs is 5 to 10 mg/kg body weight (2.3 to 4.6 mg/lb) once a day for two to three days beyond the cessation of clinical signs to a maximum of 30 days. The dose of 5 mg/kg of body weight administered once daily should be used for the routine treatment of infection caused by susceptible organism(s) in an otherwise healthy dog. The dosage may be increased to the upper limit of the dose range (10 mg/kg), if deemed necessary. For the treatment of urinary tract infections, Dicural tablets should be administered for at least 10 consecutive days. If no improvement is noted within five (5) days, the diagnosis should be re-evaluated and a different course of therapy considered. Warnings, Side Effects and Drug InteractionsDicural tablets should not be used in dogs known to be hypersensitive to quinolones. Compounds (eg, sucralfate, antacids, and multivitamins) containing divalent and trivalent cations (eg, iron, aluminum, calcium, magnesium, and zinc) may substantially interfere with the absorption of quinolones resulting in a decrease in effectiveness. Difloxacin and other quinolones have been shown to cause cartilage damage in immature animals of most species tested, the dog being particularly sensitive to this side effect. Difloxacin is contraindicated in immature dogs during the rapid growth phase (between 2 and 8 months of age in small and medium-sized breeds, and up to 18 months of age in large and giant breeds). Quinolones should be used with caution in animals with known or suspected central nervous system (CNS) disorders as, in rare instances, convulsive seizures have occurred. Quinolones have been shown to produce erosions of cartilage of weight-bearing joints and other signs of arthritis in immature animals of various species. Safety in breeding or pregnant dogs and cats has not been established. Avoid contact with eyes. If it occurs, immediately flush eyes with copious amounts of water for 15 minutes. In case of skin contact, wash skin with soap and water. Consult a physician if irritation persists following eye or skin exposure. Individuals with a history of hypersensitivity to quinolones should avoid this product. In humans, there is a risk of user photosensitization within a few hours after excessive exposure to quinolones. If excessive accidental exposure occurs, avoid direct sunlight. StorageStore Dicural tablets between 15°C and 30°C (59°F and 86°F); avoid excessive heat (40°C/104°F). ManufacturerFort Dodge Animal Health Federal law restricts this drug to use by or on the order of a licensed veterinarian.
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