Product Uses
Disal contains the active ingredient furosemide, a potent loop diuretic, which inhibits reabsorption of sodium and chloride in the kidney, to enhance water excretion. It starts to act within 30-60 minutes of oral administration. Disal tablets are indicated for the treatment of edema (fluid on the lungs or in the abdomen) associated with heart disease (along with continued use of heart stimulants) and acute non-inflammatory tissue edema.
Product Contains
furosemide
Dosage and Administration
The usual oral dosage of Disal Tablets is 1 to 2 mg/lb body weight (approximately 2.5 to 5 mg/kg). A prompt diuresis usually ensues from the initial treatment. Administer orally once or twice daily at 6 to 8 hour intervals. The dosage should be adjusted to the individual's response. In severe cases, the dose may be doubled or increased by increments of 1.0 mg per pound of body weight. The established effective dose should be administered once or twice daily.
Warnings, Side Effects and Drug Interactions
Furosemide is contraindicated in pregnant animals and may cause fetal abnormalities Furosemide is contraindicated where the animal is not passing urine, in animals allergic to the drug, in animals in a hepatic coma, or during electrolytic imbalances. The renal function, as well as levels of potassium and calcium in the blood should be monitored closely as dehydration, kidney damage and electrolyte imbalances can occur with use of the product. If given in conjunction with corticosteroids, the potassium-depletion effect of both drugs is additive. The early signs of electrolyte imbalance include: increased thirst, lethargy, drowsiness or restlessness, reduces urine production, gastrointestinal disturbances and an elevated heart rate. Potassium supplementation may be required. Excessive loss of potassium in patients receiving digitalis or its glycosides may lead to digitalis toxicity and heart arrythmias.
Diabetes may be exacerbated by furosemide. Transient loss of hearing has been experimentally produced in cats following injections into the vein of high doses of furosemide.
The concurrent use of furosemide with some antibiotics may be inadvisable as the kidney toxicity of aminoglycosides, cephalosporins and polymyxins, as well as the ototoxic effects of aminoglycosides may be increased. Sulfonamide diuretics have been reported to decrease arterial responsiveness to blood pressure raising medications and to enhance the paralytic effects of tubocurarine. It is advisable to discontinue furosemide Tablets for one day prior to any elective surgery.
Storage
Store at controlled room temperature 59-86°F.
Manufacturer
Boehringer Ingelheim
Registration Status
NADA 129-034, Approved by FDA
Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Disal
